Jennifer Aniston and Chelsea Handler Vacation Together

Actress Jennifer Aniston and E! talk show host Chelsea Handler spent Thanksgiving in their bikinis in Los Cabos, Mexico.

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Photo Credit: PRPhotos.com

“It’s Thanksgiving,” Handler tweeted Thursday. “And I am thankful for my dog, my boobies, and my life. Happy thanksgiving to you and your boobies.”

Missing from Cabo and the comedian’s tweets however, is rapper 50 Cent, who is reportedly Handler’s new man.

Handler joinined Aniston along with a group of friends for a holiday vacation. Aniston’s known for spending beach time in exotic destinations with close pals. Courteney Cox, Gerald Butler and Sheryl Crow were in Los┬áCabos to celebrate Aniston’s 41st birthday earlier this year. Spring break continues into your 40′s when you’re single – and childless.

Aniston had spent this year filming Just Go With It alongside co-star Adam Sandler. The movie centers around a man who enlists the help of a woman and her kids to find his dream woman. The romantic comedy is due to hit theaters in February 2011.

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